WHAT IS CBD?
Cannabidiol, commonly referred to as CBD is a plant cannabinoid. Humans also produce cannabinoids that are called endogenous cannabinoids. CBD has been scientifically proven to modulate and repair many physiological systems in the human brain and body using the Endocannabinoid system.
The Endocannabinoid system and Skin Conditions
Recent studies have intriguingly suggested the existence of a functional Endocannabioid system in the skin and implicated it in various biological processes (e.g. proliferation, growth, differentiation, apoptosis and cytokine, mediator or hormone production of various cell types of the skin and appendages, such as the hair follicle and sebaceous gland). It seems that the main physiological function of the Endocannabioid system is to control the proper and well-balanced proliferation, differentiation and survival, as well as immune competence and/or tolerance, of skin cells. The disruption of this delicate balance might facilitate the development of multiple pathological conditions and diseases of the skin (e.g. acne, seborrhea, allergic dermatitis, itch and pain, psoriasis, hair growth disorders, systemic sclerosis and cancer).
CBD for PSORIASIS
Psoriasis is an inflammatory disease characterized in part by an increase in keratinocyte cell production. Keratin is a fibrous protein that is crucial in forming the protective barrier that is our skin. This excessive and rapid growth of the epidermal layer of the skin generates red, itchy, and scaly patches.
The underlying mechanism of psoriasis involves the immune system. CBD acts as the messenger from the endocannabinoid system’s CB2 receptors to stimulate an anti-inflammatory response.
CBD for DERMATITIS
Cannabinoid Type 1 and 2 Receptos (CB1/2) act to suppress immune and inflammatory processes with the use of exogenous cannabinoids like CBD. Any inflammatory response in the skin due to allergens, infections, and eczema are responded by infiltrating immune cells, keratinocytes and sebocytes to bring balance back.
CBD for ACNE
The skin is lined with pores that connect to oil glands under the surface. Follicles, small sacs that produce and secrete liquid, connect the glands to the pores. These glands produce an oily liquid called sebum. Sebum carries dead skin cells to the surface of the skin through the follicles
CBD acts on human skin gland function effectively by inhibiting oil production and rapid increase in cell formation. This is through vanilloid-4 channel by influencing glucose and lipid metabolism.
CBD activates the endocannabinoid system, which includes anandamide, a neurological transmitter that regulates cell growth. When this isn’t balanced, it can negatively impact the skin. CBD also may help inhibit overactive oil production, which is one of the key causes of acne. Our sebaceous glands and hair follicles contain CB1 and CB2 receptors. These receptors work to communicate with the nervous system to produce different effects, such as reduction of inflammation and progression of acne vulgaris.